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PDE3A phosphodiesterase has been implicated in a number of physiological processes, including cardiomyocyte hypertrophy, renin release, and cardiac fibrosis. In the heart, PDE3A expression is reduced during cardiac hypertrophy, but is increased during fibrotic remodelling. Although circulating cGMP levels are low in heart failure, hearts from transgenic mice overexpressing PDE3A display increased cGMP levels and cardiac function. Administration of PDE3A inhibitors, or PDE3A gene therapy, in this model improves contractility and decreases cardiac hypertrophy and fibrosis. These studies suggest that PDE3A may be a potential target for the treatment of heart failure.Immunohistochemical localization of human chorionic gonadotropin (hCG) in human decidual tissue in vitro.
The primary objective of this study was to determine the origin of hCG in decidual tissue in vitro. Decidual tissue was obtained from 20 normal women, 6 of whom subsequently delivered between 9 and 14 days post-oocyte retrieval. Tissue specimens were fixed in formalin and embedded in paraffin. Paraffin sections were then stained by the immunoperoxidase technique. Immunostaining for hCG was detected in 8 of 20 tissue specimens. One specimen yielded both hCG-beta and hCG-alpha. The hCG staining pattern consisted of sparse cells of the stromal cell population associated with fetal vessels and no staining of the stromal cells in the connective tissue subjacent to the decidual cells. These studies demonstrate that hCG was present in decidual stromal cells and not in decidual cells.Q:
How to set tag value from a 2D vector of vector in C++?
I have a vector of vector of int values. I would like to add a specific tag to each value of the vector. I have tried using a map of hashtables as follows:
std::map > myMap;
myMap[h].insert(std::pair(t, count));
and also
std::map 0b46394aab
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