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In 2018, they are able to prove it. There are four languages, when the crew is declared inactive, he proceeds to listen to the world in all possible. Hackers, computers, you name it. I.Induction of experimental autoimmune encephalomyelitis in SJL mice by immunization with the major external glycoprotein of the herpes simplex virus.
The peripheral nervous system (PNS) is affected in 25% of the cases of Multiple Sclerosis (MS), in which it is assumed that both humoral and cell mediated responses could be involved. In this study we have investigated the ability of the glycoprotein of the herpes simplex virus to induce an experimental autoimmune encephalomyelitis (EAE) in SJL mice. Mice were immunized with purified HSV-2 glycoprotein (gp 64) and EAE was induced by immunization with myelin basic protein (MBP), (35-55) peptide. HSV-2 gp 64 induced an inflammatory response in both the central (brain) and the PNS. MBP (35-55) peptide induced T cell proliferation in vitro, and two populations of B cells were detected in the draining lymph nodes of immunized mice. HSV-2 gp 64 induced T cell lines and clones were used to analyse T cell subsets using monoclonal antibodies. The T cells obtained from HSV-2 gp 64 primed animals were divided between the CD4+ and CD8+ subsets. HSV-2 gp 64 was able to induce an EAE in SJL mice following immunization with MBP (35-55) peptide.Welcome
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